Skip to main content


Welcome to the Boston Biomedical Innovation Center application site!

The Boston Biomedical Innovation Center (B-BIC) provides funding to accelerate the development of device, diagnostic, and therapeutic solutions to heart, lung, blood, and sleep disorders.  B-BIC also supports the Mass Eye and Ear Summit Fund, translating discoveries into treatments that address vision, hearing, and balance disorders.  Applications must address unmet clinical needs to improve healthcare outcomes and aim to generate viable technologies for commercial development.  Both B-BIC and the Mass Eye and Ear Summit Fund help investigators overcome obstacles to commercial translation by funding promising technologies and positioning them to attract venture and industry partners.  Awards include financial resources in addition to business development, commercialization, and project management expertise.  

Application forms, guildelines, review criteria, and other resources can be found by clicking the resources link in the top right corner or this page.  

For general questions about the B-BIC application or review process, please contact the B-BIC Director for Operations and Finance, Lesley Watts, at (857) 307-2440 /

For questions regarding the business development aspects of your proposal, B-BIC Commercialization Coaches are available to suggest resources and provide strategic input.

Device Technologies Coach:
Paul Tessier:

Therapeutic Technologies Coach:  
John Randle, PhD:

B-BIC provides support for studies aimed at technology development and translational research, regulatory, legal, and business development expertise.  

B-BIC DRIVE grants provide up to $200,000 for direct costs to support milestone-based projects with significant involvement from the Center.  (Indirect costs are provided in accordance with the source of funding.)  DRIVE projects may take 18 - 24 months and are expected to include proof-of-value and validation studies for commercial translation of the technology.

B-BIC offers pilot grants up to $50,000 to support direct costs for one year.  (Indirect costs are provided in accordance with the source of funding.)  Pilot projects may include feasibility studies as well as experiments to test the reproducibility of hypothesis-driven research with a goal of developing the commercial value of the technology.

The Mass Eye and Ear Fund offers awards up to $300,000 to support direct costs for two years.

Faculty from member institutions are eligible to apply.  For-profit entities are eligible to apply as collaborators with Principal Investigators at member institutions.   

Deadlines and Proposal Review
Pre-proposals may be submitted anytime throughout the year.  There is no set deadline for pre-proposal submissions.  A subset of applicants who submit pre-proposals will be invited to develop full proposals.  

Full proposals are reviewed on a rolling basis by members of the External Selection Committee, including representatives from the local life sciences and venture capital communities.  Full proposals may also reviewed by our Federal Partners, including representatives from the USPTO, FDA, CMS, and payor/provider organizations.  The Federal review committee meets in March, June, September, and December. 
Confidential Information should not be included in proposals.  Do not disclose any unprotected proprietary information.  

Budget Considerations
Applications to the Pilot program may request up to $50,000 direct costs.  Applications to the DRIVE program may request up to $200,000 direct costs.  Applications to the Summit Fund may request up to $300,000 direct costs.

Indirect costs are provided at the applicant institution’s Federally-negotiated rate up to 79% MTDC for awards supported with Federal dollars. Awards supported by unrestricted funds will be provided indirect costs up to 15%.

The current NIH salary cap must be applied to personnel costs.  Funds are not awarded for the purchase of equipment, travel, tuition, or publication costs except under unusual circumstances. 

DRIVE and Summit Fund awards will be released in accordance with milestone and tranche plans included with the application. 

All pre-proposals and full proposals must be submitted using the on-line application system.

All required supporting documents, including the B-BIC budget form, compliance form, NIH biosketches, and institutional authorization must be uploaded into the on-line application system.  .pdf file format is recommended

All text material must be in a readable font (at least Arial 11 point), and margins must be at least 0.5 inches. 
Pre-Proposal Form